Formulation of an effective Pasteurella multocida vaccine for sheep.
نویسندگان
چکیده
An effective vaccine for the immunization of sheep against Pasteurella multocida infection was prepared from P. multocida Strain D4 (Type D) and a selected strain of P. multocida Type A. Provided an adequate concentration of bacteria was used, the vaccine thus formulated induced antibodies in sheep that protected mice not only against the vaccine strains but also against infection by a number of heterologous Type A and Type D strains as well as untypable strains. A locally prepared A1(OH)3 gel was found to be an effective adjuvant.
منابع مشابه
Molecular identification and capsular typing of Pasteurella multocida isolates from sheep pneumonia in Iran
Pasteurella multocida is known as one of the main organisms causing pneumonia in sheep. As immunity in pasteurellosis is serogroup specific, identification of prevalent capsular group among endemic areas is essential. The aim of this study was to molecular identification and determine of the capsular type of the P. multocida strains isolated from sheep pneumonia in Iran. Bacteriological and bio...
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عنوان ژورنال:
- The Onderstepoort journal of veterinary research
دوره 51 3 شماره
صفحات -
تاریخ انتشار 1984